DUSP6 anticorps

N° du produit ABIN1882185

Cité dans 3 publications. Cet anticorps anti-DUSP6 Polyclonal Lapin (Clone RB7281) (ABIN1882185) détecte spécifiquement DUSP6 dans WB et FACS. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour DUSP6 anticorps (ABIN1882185)

Antigène: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB7281

Détail du produit anti-DUSP6 anticorps

Purification: This antibody is purified through a protein A column, followed by dialysis against PBS.

Immunogène: This Rat MKP3 antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1~381 of rat MKP3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-DUSP6 (ABIN1882185)

Olson, Protheroe, Segar, Scholz: "Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart." dans: American journal of physiology. Heart and circulatory physiology, Vol. 290, Issue 4, pp. H1587-95, (2006) (PubMed).

Muda, Boschert, Dickinson, Martinou, Martinou, Camps, Schlegel, Arkinstall: "MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase." dans: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4319-26, (1996) (PubMed).

Mourey, Vega, Campbell, Wenderoth, Hauschka, Krebs, Dixon: "A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation." dans: The Journal of biological chemistry, Vol. 271, Issue 7, pp. 3795-802, (1996) (PubMed).

Détails sur DUSP6

Antigène: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Autre désignation: MKP3

Sujet: Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36 % identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis

Poids moléculaire: 42319

NCBI Accession: NP_446335

UniProt: Q64346

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades