Cytokeratin 18 anticorps
Aperçu rapide pour Cytokeratin 18 anticorps (ABIN1882229)
Antigène
Voir toutes Cytokeratin 18 (KRT18) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This CYK18 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 400-430 region of human CYK18.
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Isotype
- IgG3
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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: "Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." dans: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).
: "Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation." dans: Differentiation; research in biological diversity, Vol. 33, Issue 1, pp. 61-8, (1987) (PubMed).
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: "Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." dans: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Autre désignation
- CYK18
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Sujet
- Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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Poids moléculaire
- 48058
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NCBI Accession
- NP_000215, NP_954657
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UniProt
- P05783
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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