LOX anticorps (AA 234-260)

N° du produit ABIN1882262

L’anticorps Souris Monoclonal anti-LOX a été validé pour WB. Il convient pour détecter LOX dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour LOX anticorps (AA 234-260) (ABIN1882262)

Antigène: LOX (Lysyl Oxidase (LOX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LOX est non-conjugé

Application: Western Blotting (WB)

Clone: 624CT23-7-3

Détail du produit anti-LOX anticorps

Épitope: AA 234-260

Homologie: M, Pig, Rat

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.

Isotype: IgG2b

Information d'application

Indications d'application: WB: 1:100~500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-LOX (ABIN1882262)

Gao, Xiao, Ma, Li, Liu, Feng, Fang, Wu, Han, Zhang, Sun, Wu, Padera, Chen, Wong, Ge, Ji: "LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Détails sur LOX

Antigène: LOX (Lysyl Oxidase (LOX))

Autre désignation: LOX

Sujet: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 46944

NCBI Accession: NP_002308

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome