PIN1 anticorps
-
- Antigène Voir toutes PIN1 Anticorps
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
-
Reactivité
- Humain, Souris, Rat, Green Monkey
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp PIN1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- Purified His-tagged PIN1 protein was used to produced this monoclonal antibody.
- Clone
- 855CT1-7-5
- Isotype
- IgG1
- Top Product
- Discover our top product PIN1 Anticorps primaire
-
-
- Indications d'application
- WB: 1:1000. IHC-P: 1:25
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
-
- Antigène
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
- Autre désignation
- PIN1 (PIN1 Produits)
- Synonymes
- anticorps DOD, anticorps UBL5, anticorps dod, anticorps ubl5, anticorps pin1, anticorps pin1a, anticorps 0610025L01Rik, anticorps D9Bwg1161e, anticorps pin1b, anticorps zgc:73206, anticorps PPIase pin1, anticorps MdPin1, anticorps Pin1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog, anticorps protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog, anticorps peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, anticorps peptidyl-prolyl cis-trans isomerase Pin1, anticorps PIN1, anticorps Pin1, anticorps pin1, anticorps pin1.S, anticorps pin1.L, anticorps ppiD, anticorps PITG_11123, anticorps LOC103419188
- Sujet
- Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
- Poids moléculaire
- 18243
- NCBI Accession
- NP_006212
- UniProt
- Q13526
-