POU2AF1 anticorps

N° du produit ABIN1882276

Cet anticorps Souris Monoclonal détecte spécifiquement POU2AF1 dans WB. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour POU2AF1 anticorps (ABIN1882276)

Antigène: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp POU2AF1 est non-conjugé

Application: Western Blotting (WB)

Clone: 1170CT1-1-1

Détail du produit anti-POU2AF1 anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: Purified His-tagged POU2AF1 protein was used to produced this monoclonal antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-POU2AF1 (ABIN1882276)

Galiègue-Zouitina, Quief, Hildebrand, Denis, Lecocq, Collyn-dHooghe, Bastard, Yuille, Dyer, Kerckaert: "Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation." dans: Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie, Vol. 318, Issue 11, pp. 1125-31, (1996) (PubMed).

Luo, Roeder: "Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B." dans: Molecular and cellular biology, Vol. 15, Issue 8, pp. 4115-24, (1995) (PubMed).

Détails sur POU2AF1

Antigène: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Autre désignation: POU2AF1

Sujet: Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

Poids moléculaire: 27436

NCBI Accession: NP_006226

UniProt: Q16633