USP22 anticorps

N° du produit ABIN1882289

Il existe 3+ publications pour ce produit. L’anticorps anti-USP22 Monoclonal Souris est utilisé pour la détection de USP22 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour USP22 anticorps (ABIN1882289)

Antigène: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp USP22 est non-conjugé

Application: Western Blotting (WB)

Clone: 1154CT13-1-3-1

Détail du produit anti-USP22 anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: Purified His-tagged USP22 protein was used to produced this monoclonal antibody.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-USP22 (ABIN1882289)

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." dans: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Zhang, Varthi, Sykes, Phillips, Warzecha, Zhu, Wyce, Thorne, Berger, McMahon: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." dans: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).

Lee, Kim, Shin, Park, Chung, Baek: "The expression patterns of deubiquitinating enzymes, USP22 and Usp22." dans: Gene expression patterns : GEP, Vol. 6, Issue 3, pp. 277-84, (2006) (PubMed).

Détails sur USP22

Antigène: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Autre désignation: USP22

Sujet: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Poids moléculaire: 59961

NCBI Accession: NP_056091

UniProt: Q9UPT9