Cofilin 2 anticorps (AA 1-127)

N° du produit ABIN1885597

Cet anticorps Lapin Polyclonal détecte spécifiquement Cofilin 2 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Cofilin 2 anticorps (AA 1-127) (ABIN1885597)

Antigène: Cofilin 2 (CFL2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Cofilin 2 anticorps

Épitope: AA 1-127

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 127 of Cofilin 2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Cofilin 2

Antigène: Cofilin 2 (CFL2)

Autre désignation: Cofilin 2

Sujet: Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.(Gillett et al., 1996 [PubMed 8800436]).Cofilin-2 is a member of the AC group of proteins that also includes cofilin-1 (CFL1) and destrin (DSTN, MIM 609114), all of which regulate actin-filament dynamics (Bamburg et al., 1999 [PubMed 10461190], Maciver and Hussey, 2002).The CFL2 gene encodes a skeletal muscle-specific isoform (Vartiainen et al., 2002 [PubMed 11809832]) localized to the thin filaments, where it exerts its effect on actin, in part through interactions with tropomyosins (Ono and Ono, 2002 [PubMed 11901171]).[supplied by OMIM]

Poids moléculaire: 19 kDa

ID gène: 1073

Pathways: Caspase Cascade in Apoptosis