APEX1 anticorps (AA 1-15)

N° du produit ABIN1885631

L’anticorps anti-APEX1 Polyclonal Lapin est utilisé pour la détection de APEX1 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour APEX1 anticorps (AA 1-15) (ABIN1885631)

Antigène: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APEX1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-APEX1 anticorps

Épitope: AA 1-15

Purification: Affinity purified by Protein A.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur APEX1

Antigène: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Autre désignation: APE1

Sujet: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases.AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites.Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site.This gene encodes the major AP endonuclease in human cells.Splice variants have been found for this gene, all encode the same protein.[provided by RefSeq]
Synonyms: APE, APE-1, APE1, APEN, APEX, APX, HAP1, REF-1, REF1

Poids moléculaire: 36 kDa

ID gène: 328

NCBI Accession: NP_001632, NM_001641

Pathways: Réparation de l'ADN, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus