GSTM1 anticorps (AA 1-159)

N° du produit ABIN1885655

L’anticorps Lapin Polyclonal anti-GSTM1 a été validé pour WB, IHC et IF. Il convient pour détecter GSTM1 dans des échantillons de Humain.

Aperçu rapide pour GSTM1 anticorps (AA 1-159) (ABIN1885655)

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GSTM1 anticorps

Épitope: AA 1-159

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 159 of Human GSTM1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur GSTM1

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Autre désignation: GSTM1

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class.The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens.Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq]

Poids moléculaire: 21 kDa

ID gène: 2944

Pathways: Negative Regulation of Transporter Activity