PCBP2 anticorps (AA 1-163)

N° du produit ABIN1885666

Cet anticorps Lapin Polyclonal détecte spécifiquement PCBP2 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PCBP2 anticorps (AA 1-163) (ABIN1885666)

Antigène: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCBP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PCBP2 anticorps

Épitope: AA 1-163

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 163 of hnRNP E2

Information d'application

Indications d'application: Suggested dilutions:
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur PCBP2

Antigène: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Autre désignation: hnRNP E2

Sujet: The protein encoded by this gene appears to be multifunctional.Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins.The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding.Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2.This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes.Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2).Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Poids moléculaire: 38 kDa

ID gène: 5094