GSTa2 anticorps (AA 1-166)

N° du produit ABIN1885674

Cet anticorps anti-GSTa2 est un anticorps Lapin Polyclonal détectant GSTa2 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour GSTa2 anticorps (AA 1-166) (ABIN1885674)

Antigène: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTa2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GSTa2 anticorps

Épitope: AA 1-166

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 166 of Human GSTA2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur GSTa2

Antigène: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Autre désignation: glutathione S-transferase alpha 2

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class.The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver.In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.[provided by RefSeq]
Synonyms: GST2, GTA2, GTH2, GSTA2-2, MGC10525

Poids moléculaire: 26 kDa

ID gène: 2939

NCBI Accession: NP_000837, NM_000846