BCL2L1 anticorps (AA 1-178)

N° du produit ABIN1885707

Cet anticorps anti-BCL2L1 est un anticorps Lapin Polyclonal détectant BCL2L1 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour BCL2L1 anticorps (AA 1-178) (ABIN1885707)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-BCL2L1 anticorps

Épitope: AA 1-178

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 178 of BCL2L1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: BCL2L1

Sujet: The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening.VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.[provided by RefSeq]

Poids moléculaire: 26 kDa

ID gène: 598

NCBI Accession: NP_612815, NM_138578

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling