Endothelin 3 anticorps (AA 1-187)

N° du produit ABIN1885737

Cet anticorps anti-Endothelin 3 Polyclonal Lapin (ABIN1885737) détecte spécifiquement Endothelin 3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Endothelin 3 anticorps (AA 1-187) (ABIN1885737)

Antigène: Endothelin 3 (EDN3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Endothelin 3 anticorps

Épitope: AA 1-187

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 187 of Human EDN3

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Endothelin 3

Antigène: Endothelin 3 (EDN3)

Autre désignation: ET-3

Sujet: The protein encoded by this gene is a member of the endothelin family.Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.The active form of this protein is a 21 amino acid peptide processed from the precursor protein.The active peptide is a ligand for endothelin receptor type B (EDNRB).The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons.Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells.Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.[provided by RefSeq]

Poids moléculaire: 25 kDa

ID gène: 1908

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones