FANCA anticorps (AA 1-190)
Aperçu rapide pour FANCA anticorps (AA 1-190) (ABIN1885743)
Antigène
Voir toutes FANCA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-190
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 190 of FACA
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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Autre désignation
- FACA
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Sujet
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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2).The previously defined group FANCH is the same as FANCA.Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group A.Alternative splicing results in multiple transcript variants encoding different isoforms.Mutations in this gene are the most common cause of Fanconi anemia.[provided by RefSeq]
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Poids moléculaire
- 33 kDa
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ID gène
- 2175
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Pathways
- Réparation de l'ADN
Antigène
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