PFKM anticorps (AA 1-223)
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- Antigène Voir toutes PFKM Anticorps
- PFKM (phosphofructokinase, Muscle (PFKM))
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Épitope
- AA 1-223
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PFKM est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 223 of Human PFKM
- Top Product
- Discover our top product PFKM Anticorps primaire
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- Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Antigène
- PFKM (phosphofructokinase, Muscle (PFKM))
- Autre désignation
- PFK-1 (PFKM Produits)
- Synonymes
- anticorps GSD7, anticorps PFK-1, anticorps PFK1, anticorps PFKA, anticorps PFKX, anticorps AI131669, anticorps PFK-A, anticorps PFK-M, anticorps Pfk-4, anticorps Pfk4, anticorps Pfka, anticorps Pfkx, anticorps Pfk-M, anticorps M-PFK, anticorps PFKM, anticorps pfkm, anticorps zgc:92344, anticorps pfk, anticorps im:7137110, anticorps wu:fc58g11, anticorps phosphofructokinase, muscle, anticorps phosphofructokinase, platelet, anticorps phosphofructokinase, muscle a, anticorps phosphofructokinase, muscle S homeolog, anticorps phosphofructokinase, muscle b, anticorps PFKM, anticorps Pfkm, anticorps PFKP, anticorps pfkma, anticorps pfkm.S, anticorps pfkmb
- Sujet
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The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11).PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis.Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL, MIM 171860), and platelet (PFKP, MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively.The composition of the tetramers differs according to the tissue type.Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively.Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721], Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM]
- Poids moléculaire
- 85 kDa
- ID gène
- 5213
- NCBI Accession
- NM_000289, NP_000280
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg
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