F11
Reactivité: Humain
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
Biohazard Informations: This product contains thimerosal which is hazardous.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène
Factor XI (F11)
(Coagulation Factor XI (F11))
Autre désignation
Factor XI
Sujet
This gene encodes coagulation factor XI of the blood coagulation cascade.This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds.During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds.This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX.Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.[provided by RefSeq]