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RASGRP4 anticorps (AA 108-170)

RASGRP4 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1885956
  • Antigène Voir toutes RASGRP4 Anticorps
    RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 108-170
    Reactivité
    • 10
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 8
    • 3
    Lapin
    Clonalité
    • 9
    • 2
    Polyclonal
    Conjugué
    • 11
    Cet anticorp RASGRP4 est non-conjugé
    Application
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Synthetic peptide contain a sequence corresponding to a region within amino acids 108 and 170 of Human RASGRP4
    Top Product
    Discover our top product RASGRP4 Anticorps primaire
  • Indications d'application
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    Biohazard Informations: This product contains thimerosal which is hazardous.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène
    RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
    Autre désignation
    RASGRP4 (RASGRP4 Produits)
    Synonymes
    anticorps RASGRP4, anticorps RAS guanyl releasing protein 4, anticorps RASGRP4, anticorps rasgrp4, anticorps Rasgrp4
    Sujet
    The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors.It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands.This protein was shown to activate H-Ras in a cation-dependent manner in vitro.Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways.Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
    Poids moléculaire
    75 kDa
    ID gène
    115727
    NCBI Accession
    NM_170604, NP_733749
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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