MMP2 anticorps (AA 193-545)
Aperçu rapide pour MMP2 anticorps (AA 193-545) (ABIN1886151)
Antigène
Voir toutes MMP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 193-545
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 193 and 545 of Human MMP2
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Autre désignation
- MMP2
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Sujet
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes.The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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Poids moléculaire
- 74 kDa
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ID gène
- 4313
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NCBI Accession
- NM_004530, NP_004521
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Pathways
- Activation of Innate immune Response
Antigène
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