FH anticorps (AA 195-443)
Aperçu rapide pour FH anticorps (AA 195-443) (ABIN1886155)
Antigène
Voir toutes FH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 195-443
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 195 and 443 of fumarate hydratase
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- FH (Fumarate Hydratase (FH))
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Autre désignation
- fumarate hydratase
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Sujet
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The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate.It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used.The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm.It is similar to some thermostable class II fumarases and functions as a homotetramer.Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.[provided by RefSeq]
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Poids moléculaire
- 55 kDa
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ID gène
- 2271
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NCBI Accession
- NP_000134, NM_000143
Antigène
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