Exportin 2 anticorps (AA 222-439)

N° du produit ABIN1886219

L’anticorps Lapin Polyclonal anti-Exportin 2 a été validé pour WB, IF et IHC. Il convient pour détecter Exportin 2 dans des échantillons de Humain.

Aperçu rapide pour Exportin 2 anticorps (AA 222-439) (ABIN1886219)

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-Exportin 2 anticorps

Épitope: AA 222-439

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 222 and 439 of CSE1L

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Exportin 2

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Autre désignation: CSE1L

Sujet: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer.Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex.After translocation, RanGTP binds importin-beta and displaces importin-alpha.Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind.The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1.In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.[provided by RefSeq]

Poids moléculaire: 110 kDa

ID gène: 1434

NCBI Accession: NP_001307, NM_001316

Pathways: Protein targeting to Nucleus