INHBA anticorps (AA 362-423)

N° du produit ABIN1886407

Cet anticorps Lapin Polyclonal détecte spécifiquement INHBA dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour INHBA anticorps (AA 362-423) (ABIN1886407)

Antigène: INHBA (Inhibin, beta A (INHBA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INHBA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-INHBA anticorps

Épitope: AA 362-423

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 362 and 423 of Inhibin beta-A

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur INHBA

Antigène: INHBA (Inhibin, beta A (INHBA))

Autre désignation: Inhibin beta-A

Sujet: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor.Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity.In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease.Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.[provided by RefSeq]

Poids moléculaire: 47 kDa

ID gène: 3624

NCBI Accession: NM_002192, NP_002183

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy