Acetylcholinesterase anticorps (AA 406-610)

N° du produit ABIN1886446

Cet anticorps Lapin Polyclonal détecte spécifiquement Acetylcholinesterase dans WB et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Acetylcholinesterase anticorps (AA 406-610) (ABIN1886446)

Antigène: Acetylcholinesterase (AChE)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetylcholinesterase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Acetylcholinesterase anticorps

Épitope: AA 406-610

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 406 and 610 of Human ACHE

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Acetylcholinesterase

Antigène: Acetylcholinesterase (AChE)

Autre désignation: AChE

Sujet: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission.It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen.Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface.It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits.The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site.It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.[provided by RefSeq]

Poids moléculaire: 68 kDa

ID gène: 43

NCBI Accession: NP_000656, NM_000665

Pathways: Skeletal Muscle Fiber Development