MCM3 anticorps (AA 42-272)

N° du produit ABIN1886459

L’anticorps Lapin Polyclonal anti-MCM3 a été validé pour WB, IHC et IF. Il convient pour détecter MCM3 dans des échantillons de Humain.

Aperçu rapide pour MCM3 anticorps (AA 42-272) (ABIN1886459)

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MCM3 anticorps

Épitope: AA 42-272

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 42 and 272 of MCM3

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur MCM3

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Autre désignation: MCM3

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication.The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.This protein is a subunit of the protein complex that consists of MCM2-7.It has been shown to interact directly with MCM5/CDC46.This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase.The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.[provided by RefSeq]

Poids moléculaire: 91 kDa

ID gène: 4172

NCBI Accession: NM_002388, NP_002379

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA