RGS14 anticorps (AA 504-566)

N° du produit ABIN1886520

Cet anticorps anti-RGS14 Polyclonal Lapin (ABIN1886520) détecte spécifiquement RGS14 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RGS14 anticorps (AA 504-566) (ABIN1886520)

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RGS14 anticorps

Épitope: AA 504-566

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 504 and 566 of Human RGS14

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur RGS14

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Autre désignation: RGS14

Sujet: This gene encodes a member of the regulator of G-protein signaling family.This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain.The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits.Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP.This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.[provided by RefSeq]

Poids moléculaire: 61 kDa

ID gène: 10636

NCBI Accession: NM_006480, NP_006471

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling