IDH2 anticorps (AA 56-315)

N° du produit ABIN1886557

Cet anticorps Lapin Polyclonal détecte spécifiquement IDH2 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour IDH2 anticorps (AA 56-315) (ABIN1886557)

Antigène: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IDH2 anticorps

Épitope: AA 56-315

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 56 and 315 of Human IDH2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur IDH2

Antigène: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Autre désignation: IDH2

Sujet: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic.Each NADP(+)-dependent isozyme is a homodimer.The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria.It plays a role in intermediary metabolism and energy production.This protein may tightly associate or interact with the pyruvate dehydrogenase complex.[provided by RefSeq]
Synonyms: ICD-M

Poids moléculaire: 51 kDa

ID gène: 3418

NCBI Accession: NM_002168, NP_002159

Pathways: L'effet Warburg