beta Amyloid anticorps (AA 602-757)
Aperçu rapide pour beta Amyloid anticorps (AA 602-757) (ABIN1886574)
Antigène
Voir toutes beta Amyloid (Abeta) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 602-757
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 602 and 757 of Human APP
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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Autre désignation
- beta-Amyloid
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Sujet
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This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Multiple transcript variants encoding several different isoforms have been found for this gene.[provided by RefSeq]
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Poids moléculaire
- 87 kDa
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ID gène
- 351
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NCBI Accession
- NM_000484, NP_000475
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Pathways
- Inflammasome
Antigène
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