DDB1 anticorps (AA 749-1123)

N° du produit ABIN1886645

L’anticorps Lapin Polyclonal anti-DDB1 a été validé pour WB, IHC et IF. Il convient pour détecter DDB1 dans des échantillons de Humain.

Aperçu rapide pour DDB1 anticorps (AA 749-1123) (ABIN1886645)

Antigène: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-DDB1 anticorps

Épitope: AA 749-1123

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 749 and 1123 of DDB1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur DDB1

Antigène: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Autre désignation: DDB1

Sujet: This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit.This protein functions in nucleotide-excision repair.Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE).However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit.In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.[provided by RefSeq]

Poids moléculaire: 127 kDa

ID gène: 1642

NCBI Accession: NM_001923, NP_001914

Pathways: Réparation de l'ADN