Perforin 1 anticorps (AA 9-184)

N° du produit ABIN1886703

Cet anticorps anti-Perforin 1 Polyclonal Lapin (ABIN1886703) détecte spécifiquement Perforin 1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Perforin 1 anticorps (AA 9-184) (ABIN1886703)

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Perforin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Perforin 1 anticorps

Épitope: AA 9-184

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 9 and 184 of Perforin 1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Perforin 1

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Autre désignation: Perforin 1

Sujet: The protein encoded by this gene has structural and functional similarities to complement component 9 (C9).Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells.This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis.Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq]
Synonyms: HPLH2, MGC65093, P1, PFP

Poids moléculaire: 61 kDa

ID gène: 5551

NCBI Accession: NM_005041, NP_005032

Pathways: Apoptose, Caspase Cascade in Apoptosis