GFRA3 anticorps (AA 347-360)

N° du produit ABIN1886872

Cet anticorps Lapin Polyclonal détecte spécifiquement GFRA3 dans ELISA, WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GFRA3 anticorps (AA 347-360) (ABIN1886872)

Antigène: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GFRA3 anticorps

Épitope: AA 347-360

Purification: Purified by DEAE column

Immunogène: Peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur GFRA3

Antigène: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Autre désignation: GFR alpha 3

Sujet: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation.A new member of the GDNF family was recently identified and designated persephin.Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta.Following the findings of GFRalpha-1 and -2, a novel receptor in GFRalpha family was identified very recently from human and mouse and designated GFRalpha-3.GFRalpha-3 binds persephin, thus, persephin, GFRalpha-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
Synonyms: GFRa-3, GDNFRg, GDNFRgamma