GFRA1 anticorps (AA 369-382)

N° du produit ABIN1886874

Cet anticorps anti-GFRA1 Polyclonal Lapin (ABIN1886874) détecte spécifiquement GFRA1 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GFRA1 anticorps (AA 369-382) (ABIN1886874)

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GFRA1 anticorps

Épitope: AA 369-382

Specificité: The amino acid sequence of immunogenic peptide is identical to those of mouse and rat and the antibody recognizes GFR alpha 1 from human, mouse and rat origins.

Purification: Purified by DEAE column

Immunogène: Peptide corresponding to amino acids 369 to 382 of human GFR alpha 1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur GFRA1

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Autre désignation: GFR alpha 1

Sujet: Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system.Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF.The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently.GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRalpha-1 recently.GFRalpha-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK).Thus, GDNF, GFRalpha and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.
Synonyms: GFR alpha 1, GFRa-1, GDNFRa, GDNFRalpha

UniProt: P56159