GFRA2 anticorps (AA 377-391)

N° du produit ABIN1886875

Cet anticorps Lapin Polyclonal détecte spécifiquement GFRA2 dans WB, ELISA et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GFRA2 anticorps (AA 377-391) (ABIN1886875)

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-GFRA2 anticorps

Épitope: AA 377-391

Purification: Purified by DEAE column

Immunogène: Peptide corresponding to amino acids 377 to 391 of human GFR alpha 2.The amino acid sequences of immunogenic peptide are identical to those of mouse and rat.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur GFRA2

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Autre désignation: GFR alpha 2

Sujet: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation.Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN.The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently.NTNRalpha was also termed GDNFRbeta, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently.GFRalpha-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF.Thus, NTN, GFRalpha-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
Synonyms: GFRa-2, GDNFRb, GDNFRbeta

Poids moléculaire: 52 kDa