GFRA2 anticorps (AA 360-464)

N° du produit ABIN1679988

L’anticorps anti-GFRA2 Polyclonal Lapin est utilisé pour la détection de GFRA2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour GFRA2 anticorps (AA 360-464) (ABIN1679988)

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GFRA2 anticorps

Épitope: AA 360-464

Séquence: DVNVSPKGPS FQATQAPRVE KTPSLPDDLS DSTSLGTSVI TTCTSVQEQG LKANNSKELS MCFTELTTNI IPGSNKVIKP NSGPSRARPS AALTVLSVLM LKLAL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 360-464 of human GFRA2 (NP_001486.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GFRA2

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Autre désignation: GFRA2

Sujet: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.,GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2,Neuroscience,GFRA2

Poids moléculaire: 36 kDa/39 kDa/51 kDa

ID gène: 2675

UniProt: O00451