IL1RAP anticorps (AA 525-540)

N° du produit ABIN1886887

Cet anticorps Lapin Polyclonal détecte spécifiquement IL1RAP dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL1RAP anticorps (AA 525-540) (ABIN1886887)

Antigène: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1RAP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL1RAP anticorps

Épitope: AA 525-540

Réactivité croisée (Details): This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identical to those of mouse and rat origins.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur IL1RAP

Antigène: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Autre désignation: IL-1RAcP

Sujet: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP).IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment.The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP.IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP.Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response.IL-1RAcP is expressed in many tissues.
Synonyms: IL-1RAcP

Poids moléculaire: 66 kDa

Pathways: Signalisation NF-kappaB, Growth Factor Binding