FEM1B anticorps (AA 609-622)
Aperçu rapide pour FEM1B anticorps (AA 609-622) (ABIN1886892)
Antigène
Voir toutes FEM1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 609-622
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Peptide corresponding to amino acids 609 to 622 of human F1A alpha.This sequence is identical to the corresponding sequence of mouse FEM1b.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- FEM1B (Fem-1 Homolog B (FEM1B))
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Autre désignation
- F1A alpha
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Sujet
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Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family.A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1beta.F1Aalpha/FEM1beta is the homologue of C.elegans sex determining protein FEM-1.FEM-1/F1Aalpha is cleaved by CED-3 and caspase.FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1.Overexpression of F1Aalpha induces apoptosis.F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis.F1Aalpha is expressed in a variety of human and mouse tissues.
Synonyms: F1A alpha -
Poids moléculaire
- 70 kDa
Antigène
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