BNIP3L/NIX anticorps (AA 77-92)

N° du produit ABIN1886900

L’anticorps Lapin Polyclonal anti-BNIP3L/NIX a été validé pour WB, IHC et ELISA. Il convient pour détecter BNIP3L/NIX dans des échantillons de Humain.

Aperçu rapide pour BNIP3L/NIX anticorps (AA 77-92) (ABIN1886900)

Antigène: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BNIP3L/NIX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-BNIP3L/NIX anticorps

Épitope: AA 77-92

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 77 to 92 of human origin, which are identical to those of mouse Bnip3L.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur BNIP3L/NIX

Antigène: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Autre désignation: Bnip3L

Sujet: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family.A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3alpha, and Nix (for Nip3-like protein X).Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3.Overexpression of Bnip3L induces apoptosis.Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL.Bnip3L is localized in mitochondria.The messenger RNA of Bnip3L is ubiquitously expressed in human tissues.Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.
Synonyms: Nix

Poids moléculaire: 40 kDa

Pathways: Autophagy