DCAF12 anticorps (C-Term)
Aperçu rapide pour DCAF12 anticorps (C-Term) (ABIN1887065)
Antigène
Voir toutes DCAF12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 15 amino acid peptide near the carboxy terminus of human TCC52.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))
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Autre désignation
- TCC52
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Sujet
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Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types.Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors.One such CT antigen is TCC52, a novel centrosomal protein.TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.The normal biological function of this protein is not known at this time.
Synonyms: Testis cancer centrosome-related protein 52, DDB1 and CUL4 associated factor 12, DCAF12, CT102, WDR40A -
NCBI Accession
- NP_056212
Antigène
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