BUB1 anticorps (C-Term)

N° du produit ABIN1887318

Cet anticorps anti-BUB1 est un anticorps Lapin Polyclonal détectant BUB1 dans WB, ELISA et ICC. Adapté pour Humain et Rat.

Aperçu rapide pour BUB1 anticorps (C-Term) (ABIN1887318)

Antigène: BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-BUB1 anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 22 amino acid peptide from near the carboxy terminus of human Bub1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur BUB1

Antigène: BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

Autre désignation: Bub1

Sujet: Bub1 was initially identified as the mammalian homolog to the yeast protein through a cDNA screen.Bub1 encodes a kinase involved in the formation of the spindle checkpoint, an important mechanism that ensures high fidelity mitotic chromosome segregation.It is thought to be required for assembly of a functional inner centromere, sister chromatid cohesion via targeting of the Shugoshim protein and metaphase congression.Bub1 functions by phosphorylating cdc20, a member of the mitotic checkpoint complex and activating the spindle checkpoint.A related protein kinase Bub3 interacts with Bub1 and targets it to kinetochores prior to chromosome alignment.Mutations in bub1 have been associated with aneuploidy and several forms of cancer.
Synonyms: Budding uninhibited by benzimidazoles 1

UniProt: O43683