BANP anticorps (Center)

N° du produit ABIN1887517

Détail du produit anti-BANP anticorps

Antigène: BANP (Protein BANP (BANP))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BANP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the center of human BANP.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur BANP

Antigène: BANP (Protein BANP (BANP))

Autre désignation: BANP (BANP Produits)

Synonymes: anticorps smar1, anticorps smarbp1, anticorps MGC76079, anticorps MGC89601, anticorps BEND1, anticorps SMAR1, anticorps SMARBP1, anticorps AA408158, anticorps zgc:111954, anticorps BTG3 associated nuclear protein, anticorps Btg3 associated nuclear protein, anticorps BTG3 associated nuclear protein L homeolog, anticorps banp, anticorps BANP, anticorps Banp, anticorps banp.L

Sujet: BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen.BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest.p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop.BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling.Furthermore, BANP can modulate NF-kappaB transactivation and can inhibit tumorigenesis by regulating NF-kappaB target genes.Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.
Synonyms: BTG3 associated nuclear protein, BEND1, SMAR1, SMARBP1

NCBI Accession: NP_001167014