PPARG anticorps

N° du produit ABIN191899

Cet anticorps Lapin Polyclonal détecte spécifiquement PPARG dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour PPARG anticorps (ABIN191899)

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARG est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPARG anticorps

Specificité: The antibody recognizes a ~33 kDa band, corresponding to PPARgamma isoform CRA-c).

Purification: Affinity chromatography

Immunogène: Synthetic peptide surrounding amino acid 262 of human PPAR gamma isoform CRA-c

Information d'application

Indications d'application: Western blotting (0.5-4 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PPARG

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Autre désignation: PPAR-gamma

Sujet: PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPAR gamma is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism, PPARgamma also modulates insulin sensitivity, cell proliferation and inflammation. The inhibition of PPAR gamma transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARgamma.Synonyms: NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma

ID gène: 5468

NCBI Accession: NP_005028

UniProt: P37231

Pathways: Signalisation MAPK, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation