PLSCR1 anticorps

N° du produit ABIN192390

Cet anticorps anti-PLSCR1 est un anticorps Souris Monoclonal détectant PLSCR1 dans WB, IP, FACS et ICC. Adapté pour Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour PLSCR1 anticorps (ABIN192390)

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLSCR1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 13A6 [TEC-23]

Détail du produit anti-PLSCR1 anticorps

Fonction: Anti-Rt PLSCR1 Ascites

Specificité: The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.

Réactivité croisée (Details): Rat

Immunogène: Pooled lipid raft fraction isolated from RBL-2H3 cells

Isotype: IgG2a

Information d'application

Indications d'application: Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.
Flow cytometry: Intracellular staining.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilized with 15 mM sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-PLSCR1 (ABIN192390)

Smrz, Lebduska, Dráberová, Korb, Dráber: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." dans: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).

Détails sur PLSCR1

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Autre désignation: PLSCR1

Sujet: Phospholipid scramblase 1,PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.,PL scramblase 1, phospholipid scramblase 1

ID gène: 117540

UniProt: P58195

Pathways: Cellular Response to Molecule of Bacterial Origin