ADCY9 anticorps

N° du produit ABIN1944823

Cet anticorps Lapin Polyclonal détecte spécifiquement ADCY9 dans WB et IHC. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour ADCY9 anticorps (ABIN1944823)

Antigène: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCY9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ADCY9 anticorps

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000. IHC: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-ADCY9 (ABIN1944823)

Tantisira, Small, Litonjua, Weiss, Liggett: "Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways." dans: Human molecular genetics, Vol. 14, Issue 12, pp. 1671-7, (2005) (PubMed).

Small, Brown, Theiss, Seman, Weiss, Liggett: "An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation." dans: Pharmacogenetics, Vol. 13, Issue 9, pp. 535-41, (2003) (PubMed).

Hacker, Tomlinson, Wayman, Sultana, Chan, Villacres, Disteche, Storm: "Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9)." dans: Genomics, Vol. 50, Issue 1, pp. 97-104, (1999) (PubMed).

Détails sur ADCY9

Antigène: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Autre désignation: ADCY9

Sujet: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).

Poids moléculaire: 150701 Da

ID gène: 115

UniProt: O60503

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma