CDK11 anticorps

N° du produit ABIN1944862

Détail du produit anti-CDK11 anticorps

Antigène: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK11 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-CDK11 (ABIN1944862)

Gururajan, Lahti, Grenet, Easton, Gruber, Ambros, Kidd: "Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2." dans: Genome research, Vol. 8, Issue 9, pp. 929-39, (1998) (PubMed).

Xiang, Lahti, Grenet, Easton, Kidd: "Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms." dans: The Journal of biological chemistry, Vol. 269, Issue 22, pp. 15786-94, (1994) (PubMed).

Eipers, Lahti, Kidd: "Structure and expression of the human p58clk-1 protein kinase chromosomal gene." dans: Genomics, Vol. 13, Issue 3, pp. 613-21, (1992) (PubMed).

Lake, de la Cruz, Ferreira, Morel, Simpson: "Evolution of parasitism: kinetoplastid protozoan history reconstructed from mitochondrial rRNA gene sequences." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 6, pp. 2612, (1991) (PubMed).

Bunnell, Heath, Adams, Lahti, Kidd: "Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 19, pp. 7467-71, (1990) (PubMed).

Détails sur CDK11

Antigène: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Autre désignation: CDC2L1 (CDK11B Produits)

Synonymes: anticorps CDC2L1, anticorps CDK11, anticorps CDK11-p110, anticorps CDK11-p46, anticorps CDK11-p58, anticorps CLK-1, anticorps PK58, anticorps p58, anticorps p58CDC2L1, anticorps p58CLK-1, anticorps AA989746, anticorps Cdc11b, anticorps Cdc2l1, anticorps Cdc2l2, anticorps Cdk11, anticorps CDC2L2, anticorps CDK11B, anticorps cdc2l1, anticorps im:7142267, anticorps zgc:101589, anticorps cdc2l2, anticorps cdk11, anticorps cdk11-p110, anticorps cdk11-p46, anticorps cdk11-p58, anticorps cdk11b, anticorps clk-1, anticorps p58cdc2l1, anticorps p58clk-1, anticorps pk58, anticorps cyclin dependent kinase 11B, anticorps cyclin-dependent kinase 11B, anticorps cyclin-dependent kinase 11B S homeolog, anticorps CDK11B, anticorps Cdk11b, anticorps LOC489591, anticorps cdk11b, anticorps cdk11b.S

Sujet: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

Poids moléculaire: 92707 Da

ID gène: 984

UniProt: P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase