MKNK1 anticorps

N° du produit ABIN1944924

Cité dans 3 publications. Cet anticorps anti-MKNK1 Polyclonal Lapin (ABIN1944924) détecte spécifiquement MKNK1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MKNK1 anticorps (ABIN1944924)

Antigène: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKNK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MKNK1 anticorps

Isotype: IgG

Information d'application

Indications d'application: WB: 1:250-1:1000. WB: 1:250-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-MKNK1 (ABIN1944924)

OLoghlen, González, Piñeiro, Pérez-Morgado, Salinas, Martín: "Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1." dans: Experimental cell research, Vol. 299, Issue 2, pp. 343-55, (2004) (PubMed).

Knauf, Tschopp, Gram: "Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2." dans: Molecular and cellular biology, Vol. 21, Issue 16, pp. 5500-11, (2001) (PubMed).

Fukunaga, Hunter: "MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates." dans: The EMBO journal, Vol. 16, Issue 8, pp. 1921-33, (1997) (PubMed).

Détails sur MKNK1

Antigène: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Autre désignation: Mnk1

Sujet: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.

Poids moléculaire: 51342 Da

ID gène: 8569

UniProt: Q9BUB5

Pathways: Signalisation MAPK, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor