RGS10 anticorps

N° du produit ABIN1944932

Détail du produit anti-RGS10 anticorps

Antigène: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS10 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-RGS10 (ABIN1944932)

Burgon, Lee, Nixon, Peralta, Casey: "Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10)." dans: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32828-34, (2001) (PubMed).

Chatterjee, Fisher: "Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs." dans: The Journal of biological chemistry, Vol. 275, Issue 31, pp. 24013-21, (2000) (PubMed).

Hunt, Fields, Casey, Peralta: "RGS10 is a selective activator of G alpha i GTPase activity." dans: Nature, Vol. 383, Issue 6596, pp. 175-7, (1996) (PubMed).

Détails sur RGS10

Antigène: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Autre désignation: RGS10 (RGS10 Produits)

Synonymes: anticorps MGC82511, anticorps RGS10, anticorps 2310010N19Rik, anticorps regulator of G-protein signaling 10, anticorps regulator of G-protein signaling 10 L homeolog, anticorps regulator of G protein signaling 10, anticorps regulator of G-protein signalling 10, anticorps RGS10, anticorps rgs10.L, anticorps rgs10, anticorps Rgs10

Sujet: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)- alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.

Poids moléculaire: 20236 Da

ID gène: 6001

UniProt: O43665

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling