CD300E anticorps
Aperçu rapide pour CD300E anticorps (ABIN1981868)
Antigène
Voir toutes CD300E AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD300e Purified
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Réactivité croisée (Details)
- Human
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Attributs du produit
- The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
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Purification
- Purified by protein-A affinity chromatography.
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Pureté
- > 95 % (by SDS-PAGE)
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Immunogène
- CD300e-HA-transfected cells
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Isotype
- IgG1, kappa
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Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." dans: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).
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- CD300E (CD300e Molecule (CD300E))
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Autre désignation
- CD300e
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Sujet
- CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
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ID gène
- 342510
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UniProt
- Q496F6
Antigène
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