CD300E anticorps (APC)

N° du produit ABIN1981879

Détail du produit anti-CD300E anticorps (APC)

Antigène: CD300E (CD300e Molecule (CD300E))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD300E est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Specificité: The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: CD300e-HA-transfected cells

Clone: UP-H2

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CD300E (APC) (ABIN1981879)

Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." dans: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

Aguilar, Alvarez-Errico, García-Montero, Orfao, Sayós, López-Botet: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, (2004) (PubMed).

Détails sur CD300E

Antigène: CD300E (CD300e Molecule (CD300E))

Autre désignation: CD300e (CD300E Produits)

Synonymes: anticorps BC034097, anticorps CLM2, anticorps Cd300le, anticorps TREM5, anticorps CD300LE, anticorps CLM-2, anticorps CMRF35-A5, anticorps IREM-2, anticorps IREM2, anticorps PIgR-2, anticorps PIgR2, anticorps CD300E molecule, anticorps CD300e molecule, anticorps Cd300e, anticorps CD300E

Sujet: CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

ID gène: 342510

UniProt: Q496F6