MCAM anticorps (AA 50-646) (FITC)

N° du produit ABIN1991786

Détail du produit anti-MCAM anticorps (FITC)

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Épitope: AA 50-646

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCAM est conjugé à/à la FITC

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MCAM

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation: MCAM (MCAM Produits)

Synonymes: anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb

Sujet:

Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Aliases: A32 antigen antibody, CD 146 antibody, CD146 antibody, CD146 antigen antibody, Cell surface glycoprotein MUC18 antibody, Cell surface glycoprotein P1H12 antibody, Gicerin antibody, Mcam antibody, Melanoma adhesion molecule antibody, Melanoma associated antigen A32 antibody, Melanoma associated antigen MUC18 antibody, Melanoma associated glycoprotein MUC18 antibody, Melanoma cell adhesion molecule antibody, Melanoma-associated antigen A32 antibody, Melanoma-associated antigen MUC18 antibody, MelCAM antibody, MUC 18 antibody, MUC18 antibody, MUC18_HUMAN antibody, S endo 1 antibody, S endo 1 endothelial associated antigen antibody, S-endo 1 endothelial-associated antigen antibody

UniProt: P43121