KAT5 anticorps (AA 3-512) (FITC)

N° du produit ABIN1992602

L’anticorps Lapin Polyclonal anti-KAT5 a été validé pour WB et ELISA. Il convient pour détecter KAT5 dans des échantillons de Humain.

Aperçu rapide pour KAT5 anticorps (AA 3-512) (FITC) (ABIN1992602)

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT5 est conjugé à/à la FITC

Application: Western Blotting (WB), ELISA

Détail du produit anti-KAT5 anticorps (FITC)

Épitope: AA 3-512

Fonction: KAT5 Antibody, FITC conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Histone acetyltransferase KAT5 protein (3-512AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KAT5

Antigène: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Autre désignation: KAT5

Sujet:

Background: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Aliases: 60 kDa Tat interactive protein antibody, 60 kDa Tat-interactive protein antibody, cPLA(2) interacting protein antibody, cPLA(2)-interacting protein antibody, cPLA2 antibody, cPLA2 interacting protein antibody, ESA1 antibody, Histone acetyltransferase HTATIP antibody, Histone acetyltransferase KAT5 antibody, HIV 1 Tat interactive protein antibody, HIV 1 Tat interactive protein, 60 kDa antibody, HIV-1 Tat interactive protein antibody, HTATIP antibody, HTATIP1 antibody, K(lysine) acetyltransferase 5 antibody, K-acetyltransferase 5 antibody, KAT5 antibody, KAT5_HUMAN antibody, Lysine acetyltransferase 5 antibody, PLIP antibody, Tat interacting protein, 60 kDa antibody, TIP antibody, Tip60 antibody

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway