CD130/gp130 anticorps

N° du produit ABIN206053

Cet anticorps Souris Monoclonal détecte spécifiquement CD130/gp130 dans ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD130/gp130 anticorps (ABIN206053)

Antigène: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD130/gp130 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Détail du produit anti-CD130/gp130 anticorps

Specificité: Recognizes soluble and membrane bound gp130 receptor, also known as CD130, Interleukin-6 receptor subunit beta, Oncostatin-M receptor subunit alpha or Interleukin-6 signal transducer. CD130 is a 918 amino acid, ~130 kD single pass type-1 transmembrane glycoprotein containing a single and multiple domains. CD130 can be cleaved to form a monomeric soluble ~100 kD form of the receptor detectable in plasma and other biologic fluids where it acts as an IL-6 antagonist. Binds to an epitope dependent at least partially on the presence of the Ig-like domain. Has been reported to block receptor activity and inhibit IL-6 induced proliferation of XG1 cells and IL-27 mediated proliferation of naive CD4+ T cells,.

Purification: Ion exchange chromatography

Immunogène: Natural soluble gp130 receptor.

Type of Immunogen: Purified protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CD130/gp130

Antigène: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Autre désignation: CD130 / IL6ST / Gp130

Sujet: Name/Gene ID: IL6ST
Family: Interleukin

Synonyms: IL6ST, CD130, CD130 antigen, IL-6R subunit beta, IL-6 receptor subunit beta, Membrane glycoprotein gp130, Membrane glycoprotein 130, IL-6RB, CDW130, gp130, IL-6R-beta

ID gène: 3572

Pathways: Signalistation JAK/STAT, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints