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Androgen Receptor anticorps (pSer213)

L’anticorps Souris Monoclonal anti-Androgen Receptor a été validé pour WB. Il convient pour détecter Androgen Receptor dans des échantillons de Humain et Singe.
N° du produit ABIN207872

Aperçu rapide pour Androgen Receptor anticorps (pSer213) (ABIN207872)

Antigène

Voir toutes Androgen Receptor (AR) Anticorps
Androgen Receptor (AR)

Reactivité

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Humain, Singe

Hôte

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Souris

Clonalité

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Monoclonal

Conjugué

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Cet anticorp Androgen Receptor est non-conjugé

Application

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Western Blotting (WB)

Clone

156C135-2
  • Épitope

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    AA 207-221, pSer213

    Specificité

    In IGF-1 stimulated LNCaP cells (passage number 38), a ~110 kD band was observed. Please see Lin et al. 2003 for additional details. The serine phosphorylation site recognized by this has been alternatively referred to Ser213 (Lee and Chang, 2003) and Ser210 (Lin et al, 2003). Variations in denotation can arise from how the sequence is counted in various GenBank accession numbers. The site is denoted as Ser213 in GenBank Accession No. A39248, which was used to design the immunogen.

    Homologie

    Percent identity by BLAST analysis: Human, Chimpanzee, Baboon, Monkey, Marmoset (100%) Gorilla, Bat, Panda (93%) Dog, Bovine, Cat, Rabbit, Horse, Pig, Guinea pig (87%) Mouse, Rat, Hamster (80%).

    Purification

    Protein G purified

    Immunogène

    This antibody was developed against a synthetic peptide corresponding to amino acids 207-221 (GRAREAS*GAPTSSKD) of human androgen receptor, containing the serine 213 phosphorylation site: GenBank Accession No. A39248. Note: S* refers to phosphorylated serine in the peptide sequence. Percent identity by BLAST analysis: Human, Chimpanzee, Baboon, Monkey, Marmoset (100%), Gorilla, Bat, Panda (93%), Dog, Bovine, Cat, Rabbit, Horse, Pig, Guinea pig (87%), Mouse, Rat, Hamster (80%).

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Indications d'application

    Approved: WB (1 - 4 μg/mL)

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.2 % gelatin, 0.05 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-80 °C

    Stockage commentaire

    Short term: 4°C
    Long term: -70°C.
  • Antigène

    Androgen Receptor (AR)

    Autre désignation

    AR / Androgen Receptor

    Sujet

    Name/Gene ID: AR
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: AR, Androgen receptor, Dihydrotestosterone receptor, DHTR, AIS, KD, NR3C4, HUMARA, SBMA, TFM, SMAX1, HYSP1

    ID gène

    367

    UniProt

    P10275

    Pathways

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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